Peramivir Intermediate III

Methyl 3-[(1R)-1-amino-2-ethylbutyl]-4-{[(tert-butoxy)carbonyl]amino}-2-hydroxycyclopentane-1-carboxylate

CAS: 316173-29-2

Molecular Formula: C18H34N2O5

Peramivir Intermediate III - Names and Identifiers

Name	Methyl 3-[(1R)-1-amino-2-ethylbutyl]-4-{[(tert-butoxy)carbonyl]amino}-2-hydroxycyclopentane-1-carboxylate
Synonyms	Peramivir Impurity 12 Peramivir Intermediate 3 Peramivir Intermediate III 4R)-Methyl 3-((R)-1-aMino-2-ethylbutyl)-4-(tert-butoxycarbonylaMino)-2-hydroxycyclopentanecarboxylate Methyl 3-[(1R)-1-amino-2-ethylbutyl]-4-{[(tert-butoxy)carbonyl]amino}-2-hydroxycyclopentane-1-carboxylate (1S,2S,3S,4R)-Methyl-((R)-1-amino-2-ethylbutyl)-4-(tert-butoxycarbonylamino)-2-hydroxycyclopentanecarboxylate (1S,2S,3S,4R)-Methyl 3-((R)-1-aMino-2-ethylbutyl)-4-(tert-butoxycarbonylaMino)-2-hydroxycyclopentanecarboxylate (1S,2S,3S,4R)-Methyl 3-((S)-1-aMino-2-ethylbutyl)-4-(tert-butoxycarbonylaMino)-2-hydroxycyclopentanecarboxylate (1S,2S,3S,4R)-Methyl 3-((R)-1-amino-2-ethylbutyl)-4-(tert-butoxycarbonylamino)-2-hydroxycyclopentanecarboxylate (1S,2S,3S,4R)-Methyl-3-((R)-1-amino-2-ethylbutyl)-4-(tert-butoxycarbonyl)amino)-2-hydroxycyclopentanecarboxylate (1S,2S,3S,4R)-Methyl 3-((R)-1-amino-2-ethylbutyl)-4-((tert-butoxycarbonyl)amino)-2-hydroxycyclopentanecarboxylate methyl (1S,2S,3S,4R)-3-[(1R)-1-amino-2-ethylbutyl]-2-hydroxy-4-[(2-methylpropan-2-yl)oxycarbonylamino]cyclopentane-1-carboxylate (1S,2S,3S,4R)-3-[(1S)-1-AMino-2-ethylbutyl]-4-[[(1,1-diMethylethoxy)carbonyl]aMino]-2-hydroxycyclopentanecarboxylic Acid Methyl Ester (1S,2S,3S,4R)-3-[(1S)-1-Amino-2-ethylbutyl]-4-[[(1,1-dimethylethoxy)carbonyl]amino]-2-hydroxy-cyclopentanecarboxylic acid methyl ester
CAS	316173-29-2
EINECS	1308068-626-2
InChI	InChI=1S/C18H34N2O5/c1-7-10(8-2)14(19)13-12(20-17(23)25-18(3,4)5)9-11(15(13)21)16(22)24-6/h10-15,21H,7-9,19H2,1-6H3,(H,20,23)/t11-,12+,13+,14+,15+/m0/s1

Peramivir Intermediate III - Physico-chemical Properties

Molecular Formula	C18H34N2O5
Molar Mass	358.47
Density	1.10±0.1 g/cm3(Predicted)
Boling Point	476.5±45.0 °C(Predicted)
pKa	11.63±0.70(Predicted)

Peramivir Intermediate III - Introduction

Compound Name: Methyl 3-[(1R)-1-amino-2-ethylbutyl]-4-{[(tert-butoxy)carbonyl]amino}-benzyl

Common Name: Methyl Formate

Nature:
-molecular formula: C15H29NO5
-Molecular weight: 307.40g/mol
-Appearance: colorless liquid
-Important chemical properties: Methyl formate is an ester compound, which is volatile, flammable and irritating. It is soluble in organic solvents at room temperature and pressure and has a champagne flavor.

Use:
Methyl formate is commonly used as a solvent and raw material in organic synthesis. It can also be used as a food extraction solvent for the extraction and preparation of spices and food additives.

Method:
Methyl formate can be formed by the reaction of methanol and formic acid. Common synthetic methods include transesterification, esterification and methyl esterification.

Safety Information:
Methyl formate is a flammable liquid, should be stored in a cool, ventilated place, away from fire and high temperature. Use should pay attention to fire and explosion. Contact with the skin and eyes may cause irritation, should avoid direct contact. Personal protective equipment such as gloves, goggles and protective clothing should be worn during use. If inhaled or ingested, seek medical attention immediately.

Last Update：2024-04-09 02:00:45